制药工程系-孙艳

发布者:系统管理员发布时间:2020-12-25浏览次数:156

个人简介

孙艳,女,1974年5月,博士,硕导

◆ 研究方向:

纳米多孔材料在生物、制药和环境领域的应用研究

◆ 教育经历:

1992.08-1996.07 大连理工大学化工学院       化学工程专业         工学学士

1996.08-1997.07 大连理工大学信息工程学院   计算机应用专业       双学士

1997.08-2004.02 中科院大连化学物理研究所     化学工程专业       工学博士

◆ 工作经历:

2004.03-2005.05  中科院大连化学物理研究所生物技术部             助理研究员

2005.05-2006.06  西班牙纳瓦拉大学药学院纳米药物技术实验室       博士后

2006.07-2013.07  哈尔滨工业大学理学院/yh533388银河           副教授

2013.09-2019.07  哈尔滨工业大学城市水资源与水环境国家重点实验室   博士后

2019.09-         yh0388银河               副教授

◆ 科研教研项目:

   1.导电介孔纳米颗粒复合界面聚合膜制备与水处理性能研究,中国博士后科学基金面上项目(2014M561359). 2015/01-2018/12,主持人

   2.具有"门禁"、孔道修饰和形貌可控介孔氧化硅纳米颗粒应用于siRNA靶向转染与控制释放的研究,国家自然科学基金青年基金(30900336),2010/01-2012/12,主持人

   3.应用介孔氧化硅纳米颗粒介导靶向转染与控制释放,教育部博士点新教师基金(20092302120070),主持人

   4.:新型基因载体介孔氧化硅材料的研究,黑龙江省教育厅科学技术研究项目,2010/01-2012/12,主持人

   5.介孔纳米材料对微污染水体中抗生素的吸附研究,城市水资源与水环境国家重点实验室开放研究基金重点项目(QAK200809),2009/01-2013/12,主持人

   6.抗肿瘤基因转运纳米载体的合成表征及机制研究,哈尔滨市创新人才基金(2007RFLXS012),2008/01-2010/12,主持人

   7.: 配体修饰的纳米载体/基因复合物的形态学和转基因研究,哈尔滨工业大学科研创新基金,2008/01-2010/12,主持人

   8.突变型乳酸脱氢酶文库的构建、表达和表征,中国科学院大连化学物理研究所博士探索基金,2004/03-2005/03,主持人

◆ 代表论文:

1.  Qi Zhao,Dongwei Lu,Yumeng,Zhao,Yan Sun,Zhuoyu Li,Mo Yang,Panpan Wang,Jun Ma.Peroxymonosulfate-based cleaning technology for metal oxide-coated ceramic ultrafiltration membrane polluted by Alcian Blue 8GX dye: Radical and non-radical oxidation cleaning mechanism. Journal of Membrane Science,2019, 573:210-217

2.Yang,Mo;Lu,Dongweii;Yang,Jiaxuan;Zhao,Yumeng;Zhao,Qi;Sun,Yan;Liu,Huiling;Ma,Jun.Carbon and nitrogen metabolic pathways and interaction of cold-resistant heterotrophic nitrifying bacteria under aerobic and anaerobic conditions. Chemosphere, 2019, 234:162-170

3.  刘献斌,谢欣欣,燕红,孙晓君,孙艳*.介孔炭材料及介孔炭/氧化硅复合材料对大分子有机污染物的吸附A review of the adsorption of organic pollutants on mesoporous carbons and carbon/silica hybrids, 新型炭材料,2013(4):241-245

Yang,Mo;Lu,Dongweii;Yang,Jiaxuan;Zhao,Yumeng;Zhao,Qi;Sun,Yan;Liu,Huiling;Ma,Jun.

4.  Liu, Xianbin, Sun, Yan*, Tang, Shiyang, Sun, Xiaojun. Novel synthesis of the monodisperse mesoporous silica nanoparticles under reflux condition, Abstracts of Papers, Oral, 243rd ACS National Meeting & Exposition, San Diego, CA, United States, March 25-March 29, 2012, COLL-559

5.  Lu, Xiaoguang, Sun, Yan*, Lin, Li, Ding, Yong, Tang, Shiyang, Liu, Xianbin. Designed a novel siRNA delivery system using the monodisperse mesoporous silica nanoparticles as nanovehicle. Abstracts of Papers, Oral, 243rd ACS National Meeting & Exposition, San Diego, CA, United States, March 25-March 29, 2012, COLL-674.

6.  Yan Sun. Rheological approach to targeting phenomena of lipoplexes (review). Current Drug Discovery Technologies, 2011, 8(4): 340-356 (约稿,PubMed收录)

7.  唐诗洋, 孙晓君, 林丽, 孙艳*, 刘献斌. 单分散介孔氧化硅纳米颗粒的制备及其在生物材料方面的应用. 化学进展, 2011, 23(9), 1973-1984

8.  Conchita Tros de Ilarduya*, Yan Sun, Nejat Düzgüneş. Gene delivery by lipoplexes and polyplexes (review). European Journal of Pharmaceutical Sciences, 2010, 40(3): 159-170 (撰写人,SCI高被引论文,本领域TOP 1% 论文)

9.  Yan Sun, Itziar Miguéliz, Gemma Navarro, Conchita Tros de Ilarduya. Structural and Morphological Studies of Cationic Liposomes-DNA Complexes. Letters in Drug Design & Discovery, 2009, 6(1): 33-37

10.Yan Sun*, Lei Fu, Zhiqiang Xu, chongfei Xu, Qian Yang. Effect of Molecular Weight and Charge Ratio on the Stability of the Chitosan/DNA Complexes. Journal of biotechnology, 2008, 136S: S178

11.Yan Sun*, Xingju Yu, Yasuyuki Takaoka, Sho-ichi Ohi, Nejat Düzgüneş, Sadao Hirota. Comparison of shape of DNA-cationic lipid complexes and model polyelectrolyte-lipid complexes. Journal of Colloid and Interface Science, 2004; 276(2): 317-322

12.Yan Sun, Xuetuo Li, Xingju Yu*. 高效液相色谱法测定番泻甙及其代谢产物番泻素. 色谱, 2004, 22 (1): 48-50

13.Yan Sun, Xuetuo Li, Nejat Düzgüneş, Yasuyuki Takaoka, Sho-ichi Ohi, Sadao Hirota*. The shape parameter of liposomes and DNA-lipid complexes determined by viscometry utilizing small sample volumes. Biophysical Journal 2003; 85(2): 1223-1232

14.Jin-Xia Fan, Xiao-Xue Yang, Jin-Zhu Song, Xiao-Mei Huang, Zhong-Xiang Cheng, Lin Yao, Olivia S. Juba, Qing Liang, Qian Yang , Margaret Odeph, Yan Sun, Yun Wang. Heterologous Expression of Transaldolase Gene Tal from Saccharomyces cerevisiae in Fusarium oxysporum for Enhanced Bioethanol Production. Appl Biochem Biotechnol 2011, 164:1023–1036

15.Jin-xia Fan, Qian Yang, Zhi-hua Liu, Xiao-mei Huang, Jin-zhu Song, Zhong-xiang Chen, Yan Sun, Qing Liang, Shuang Wang. The characterization of transaldolase gene tal from Pichia stipitis and its heterologous expression in Fusarium oxysporum Mol Biol Rep. 2011, 38:1831–1840

16.P Yang, Q Yang, J Song, Y Sun, Y Wang. Isolation of sequences flanking the Trichoderma asperellum task1 gene using a single specific primer PCR and their use for gene knockout. Annal of Microbiology, 2012, 62(4):1557-1564

17.Bo Liu, Yan Sun, Yonghong Li, Zongbao Zhao. Progress on microbial glyceride biosynthesis and metabolic regulation in oleaginous microorganisms. Acta Microbiologica Sinica, 2005, 45(1): 153-156

18.李永红,刘波,孙艳,赵宗保,白凤武. 广谱碳源产油酵母菌的筛选,中国生物工程杂志,2005,25(12): 39-44

19. Yan Sun, Bo Liu, JingMei Zhao, HaiYan Wang, SuLan Yin, XueTuo Li. Effect of preparation of spirulina on intestinal flora of diabetic. 沈阳药科大学学报, 2003, 20 (4): 299-301

20.Yan Sun, Bo Liu, Jingmei Zhao, Haiyan Wang, Heli Xu, Xuetuo Li. 大连地区糖尿病患者与健康成年人肠内菌群的比较. 世界华人消化杂志, 2003; 11(6): 863-865

21. Yan Sun, Xuetuo Li, Sulan Yin. 肠道内微生态环境对中草药体内代谢的影响. 中草药, 2001, 32(4): 375-377

22. Yan Sun, Qi Hu, Xuetuo Li. The current situation and the development prospect of the urban environmental protection techniques in our country. 大连理工大学学报, 2000, 21(s1): 48-51